Carequality is a national-level, consensus-built, interoperability framework to enable exchange between and among health information networks. Carequality brings together diverse groups, including electronic health record vendors, record locator service providers and other types of existing networks, to determine technical and policy agreements to enable data to flow between and among networks, platforms and geographies. The Carequality Framework provides the essential elements for trusted national exchange, such as common rules of the road (including a Trusted Exchange Framework), well-defined technical specifications and a participant directory.